Find out about Horner syndrome, an interruption in nerve signals from the brain to the eye and face on one side of the body.
Horner syndrome is a condition that affects the face and eye on one side of the body. It is caused by the disruption of a nerve pathway from the brain to the head and neck.
Typically, signs and symptoms of Horner syndrome include decreased pupil size, a drooping eyelid and decreased sweating on the affected side of the face.
Horner syndrome may be the result of another medical problem, such as a stroke, tumor or spinal cord injury. In some cases, no underlying cause can be found. There's no specific treatment for Horner syndrome, but treatment for the underlying cause may restore nerve function.
Horner syndrome is also known as Bernard-Horner syndrome or oculosympathetic palsy.
Horner syndrome usually affects only one side of the face. Common signs and symptoms include:
Signs and symptoms, particularly ptosis and anhidrosis, may be subtle and difficult to detect.
Additional signs and symptoms in children with Horner syndrome may include:
A number of factors, some more serious than others, can cause Horner syndrome. It is important to get a prompt and accurate diagnosis.
Get emergency care if signs or symptoms associated with Horner syndrome appear suddenly, appear after a traumatic injury, or are accompanied by other signs or symptoms, such as:
Horner syndrome is caused by damage to a certain pathway in the sympathetic nervous system. The sympathetic nervous system regulates heart rate, pupil size, perspiration, blood pressure and other functions that enable you to respond quickly to changes in your environment.
The nerve pathway affected by Horner syndrome is divided into three groups of nerve cells (neurons).
This neuron pathway leads from the hypothalamus at the base of the brain, passes through the brainstem and extends into the upper portion of the spinal cord. Problems in this region that can disrupt nerve function related to Horner syndrome include:
This neuron path extends from the spinal column, across the upper part of the chest and into the side of the neck. Causes related to nerve damage in this region may include:
This neuron path extends along the side of the neck and leads to facial skin and muscles of the iris and eyelids. Nerve damage in this region may be associated with the following:
The most common causes of Horner syndrome in children include:
In some cases, the cause of Horner syndrome cannot be identified. This is known as idiopathic Horner syndrome.
In addition to a general medical examination, your doctor will likely conduct tests to determine the nature of your symptoms and identify a possible cause.
Your doctor may be able to diagnose Horner syndrome based on your history and an assessment of your symptoms.
An eye specialist (ophthalmologist) may also confirm a diagnosis by putting a medicated eye drop in both eyes — either a drop that will dilate the pupil of a healthy eye or a drop that will constrict the pupil in a healthy eye. By comparing the reactions in the healthy eye with that of the suspect eye, the doctor can determine whether nerve damage is the cause of problems in the suspect eye.
The nature of your symptoms may help your doctor narrow the search for the cause of Horner syndrome. Your doctor may also conduct additional tests or order imaging tests to locate the lesion or irregularity disrupting the nerve pathway.
Your doctor may administer a type of eye drop that will significantly dilate the healthy eye and little dilation of the affected eye if Horner syndrome is caused by a third-order neuron irregularity — a disruption somewhere in the neck or above.
Your doctor may order one or more of the following imaging tests to locate the site of a probable irregularity causing Horner syndrome:
There's no specific treatment for Horner syndrome. Often, Horner syndrome disappears when an underlying medical condition is effectively treated.
In most nonemergency situations, you typically start by seeing a family doctor or an (ophthalmologist). You may be referred to a doctor who specializes in nervous system disorders (neurologist) or a specialist in both neurological disorders and disorders affecting the eye and visual pathways (neuro-ophthalmologist).
Before your appointment, make a list that includes the following:
Take a family member or friend along, if possible, to help you remember the information you're given.
Basic questions to ask your provider include:
If possible, bring some relatively recent photographs — ones that were taken before the onset of symptoms — to your appointment. These images may help your doctor assess the current condition of your affected eye.
Your doctor is likely to take a history of your symptoms and conduct a general medical examination. He or she is likely to ask you a number of questions, including: