Premenstrual dysphoric disorder

A severe, sometimes disabling extension of PMS.


The cause of PMDD isn't clear. It's possible that hormonal changes worsen underlying mood disorders such as anxiety and depression.


PMDD causes extreme mood shifts that can disrupt work and damage relationships. Symptoms include extreme sadness, hopelessness, irritability, or anger, plus common PMS symptoms.


Prescription drugs and lifestyle changes may help.

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