A condition in adults in which the pituitary gland makes too much growth hormone.


A rare condition that happens when the body makes too much growth hormone during adulthood.


With acromegaly, the bones in the hands, feet and face grow in size. The cause is most often a tumor of the pituitary gland. The tumor isn't cancer. But it leads the pituitary gland to make too much growth hormone over a long amount of time. In a few people with acromegaly, tumors in other parts of the body cause the condition.


Acromegaly symptoms often are different from one person to another. The hands and feet may grow. The facial bones, lips, tongue and nose may get bigger. Skin may become coarse, oily and thicker. Sweating and body odor may happen more than usual. Other symptoms can include small skin growths, tiredness, and weakness in the joints or muscles.


Acromegaly treatment depends on various factors. These factors include age, overall health, the location and size of the tumor, and how serious the symptoms are. Surgery can remove some or all of the tumor. Radiation may be used to destroy any leftover tumor cells. Medicines can help hormones return to regular levels.

© 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. | Terms of Use